Jose Mourinho has included a host of big names, including three summer arrivals Mark Schwarzer, Marco van Ginkel and Andre Schurrle, for the club's upcoming trip.
Youngster Tomas Kalas been forced to withdraw through injury, but summer arrivals Mark Schwarzer, Marco van Ginkel and Andre Schurrle are all included.
Belgium international duo Kevin De Bruyne and Romelu Lukaku also feature after impressing since returning from loans spells at Werder Bremen and West Brom.
Chelsea's first match is against Serie A giant Inter Milan on Friday in Indianapolis in its ICC opener, before facing either AC Milan or Valencia in the next round, and one of Real Madrid, Juventus, Everton and the LA Galaxy in its final ICC game. The club concludes its second U.S. trip this offseason against Roma at RFK Stadium in Washington, D.C., on Aug. 10.
Chelsea has won all three of its preseason games since Mourinho returned to Stamford Bridge - beating Singh All-Stars 1-0, Malaysia XI 4-1 and Indonesia All-Stars 8-1.
Here is the club's 25-man travel squad:
Petr Cech, Mark Schwarzer, Hilario, Jamal Blackman, Branislav Ivanovic, Ashley Cole, Gary Cahill, John Terry, Cesar Azpilicueta, Ryan Bertrand, David Luiz, John Mikel Obi, Michael Essien, Oscar, Ramires, Frank Lampard, Marco van Ginkel, Eden Hazard, Juan Mata, Victor Moses, Andre Schurrle, Kevin De Bruyne, Fernando Torres, Romelu Lukaku, Demba Ba.