United will look to make it three straight wins on the road when Ben Olsen's side faces struggling San Jose.
After going into the World Cup break with a 4-2 win in Montreal, United last weekend notched a 2-1 triumph at Toronto FC. Ironically, first-place D.C. (8-5-4) dropped its only home game during this stretch, a 1-0 loss to the Seattle Sounders coming out of the hiatus.
The Earthquakes (4-7-4), meanwhile, are struggling, with three straight losses dropping them to last place in the Western Conference.
United will again be without Fabian Espindola (knee), with Jeff Parke (foot) a question mark. For the Earthquakes, midfielder Shea Salinas (abdomen) is questionable.