Philadelphia will look to avenge last season's heavy loss to New England when the Revs visit PPL Park.
The Revolution lost 4-0 to the Houston Dynamo last week, the biggest margin of any game in MLS' opening week. Despite being tabbed by many as a preseason dark horse, New England had no response to the Will Bruin-led attack.
Philadelphia was deprived of a win at Portland only by a last-minute Gaston Fernandez goal, but otherwise turned in an encouraging performance. The Union will have been pleased with the perfomances of their new players, especially Maurice Edu, who provided the powerful midfield presence the Union have been lacking and assisted Jack McInerney's goal.
In 10 meetings all-time, the Union have been the usual beneficiary, taking five wins to New England's two with three draws. Those two Revolution wins, however, came in the last two meetings. After a 1-0 Philly win last March, the Revolution responded with a 2-0 win and a resounding 5-2 thrashing.
The Union could welcome back Sheanon Williams and Conor Casey, both of whom missed last week's game against Portland with quad strains.
The Revs could be missing a number of players, including Andrew Farrell (tibial stress reaction), Lee Nguyen (groin strain), Andy Dorman (concussion), Jose Goncalves (quad strain), Saer Sene (ankle surgery) and Chris Tierney (hamstring strain).