The German side ran to comfortable win over the French outfit, making up for a loss in the club's first outing.Borussia Dortmund picked up its first points of this season's Champions League courtesy of a 3-0 win over Olympique de Marseille on Tuesday.
Robert Lewandowski, who netted a double, and Marco Reus were the men on target as the home side got its first-ever win in the competition against the French side.
Poland international Lewandowski put the finishing touches to a well-worked team goal after 19 minutes before Reus' free kick found its way into the back of the net seven minutes after the break.
Lewandowski then added a third from the spot late on to wrap up the victory.
The home side - which was watched by coach Jurgen Klopp from the stands as he served a one-match touchline ban for his protests in the defeat against Napoli - was without goalkeeper Roman Weidenfeller following a red card in the Group F opener, while Eric Durm replaced the injured Marcel Schmelzer.
Marseille was once again without striker Andre-Pierre Gignac, who has been sidelined with a toe injury.
Both sides came into the game off the back of domestic wins at the weekend – against Lorient and Freiburg respectively - but it was Dortmund which began the brighter, with Reus firing narrowly over in the second minute before forcing a save from Steve Mandanda.
However, Marseille had strong claims for a penalty turned down shortly afterwards when Saber Khelifa went down under a challenge from Durm.
Dortmund eventually went ahead through a goal of the highest quality after 18 minutes, with Lewandowski netting his third goal in four days.
After a quick break, Reus played in Henrikh Mkhitaryan. He fired across goal to Durm, who in turn put the ball on a plate for the Pole to cap off a wonderfully worked team goal.
While Dortmund continued to enjoy plenty of possession, the club struggled to create too many other clear-cut chances before the break.
However, the team was two goals ahead six minutes after the interval after a Reus free kick forced Mandanda into a costly error.
The goalkeeper flapped at the inswinging delivery and, while he tried desperately to claw the ball out, his efforts proved futile as the ball crept in and Dortmund doubled the lead.
Mandanda then went some way to atoning for his error, producing a smart stop to deny Durm from close range after 58 minutes.
But Lewandowski made it three 10 minutes from time from the penalty spot after Reus had been pulled down by Khelifa in the area to cap off a comfortable victory for Klopp's men.