Guy Poyet's Black Cats are paying $2.20 at bet365 to win at the Stadium of Light, with the visitors priced at $3.75 and the draw worth $3.30.
The home side are being backed in to come out on top despite having not won for six matches, but were unfortunate to go down 2-1 away to Liverpool last time out.
They are badly in need of points, sitting second bottom on the table and four points from the safety of 17th place.
West Ham are sitting pretty by comparison in the relative safety of 11th, although still only eight points clear of the drop.
Sam Allardyce's men registered a 2-1 win at home to Hull City last time out.
The last meeting between these two ended in a 0-0 draw at Upton Park in December, and you can get $9.00 on a repeat of that scoreline.
The previous meeting in the northeast produced a comfortable 3-0 win for Sunderland, with that score worth $21.00 at bet365.
Adam Johnson was among the scorers in that fixture last January, and you can get $8.00 on him opening the scoring on Monday, or $3.40 to score at any time.