Roberto Martinez's men are not expected to back-up their milestone Old Trafford win, while it's tough to separate two other teams batting in the wrong half of the table
Roberto Martinez's team are the $5.00 outsiders at the Emirates Stadium, with Arsene Wenger's hosts paying $1.66 and the draw at $3.75.
For those punters who also expect Arsenal to get up, but believe Everton will give a good account of themselves, the half-time/full time market could be of interest, with Arsenal paying $4.50 to be drawing at the break, before going on to win the game.
Gunners front-man Olivier Giroud occupies the top line of betting in the first goal-scorer market at $5.50, with in-form Everton striker Romelu Lukaku, on loan from Chelsea, paying $6.50.
Lukaku netted twice in Everton's dramatic 3-3 draw with Liverpool last month, and bet365 are paying $10.00 for him to bag a brace at the Emirates.
In the earlier game on Sunday, it's a tight one between Fulham ($2.62) and Aston Villa ($2.62), with the draw at $3.30.
Fulham, now under Rene Meulensteen after the dismissal of Martin Jol, were unfortunate to lose 2-1 at home Tottenham Hotspur last time out, while Aston Villa managed a 3-2 victory away to Southampton, leaving the bookies unable to separate these two sides.
Villa's Austrian attacking midfielder Andreas Weimann is tempting in the first goal-scorer reckoning at $7.50, with Fulham's Darren Bent ($8.00) a chance to score against his former team.