The Spanish capital will be divided down the middle this weekend, as Carlo Ancelotti's team - the heavy favourites - prepare to hose their cross city rivals at the Bernabeu
Atletico Madrid are heavy underdogs in Saturday's Madrid derby against Real despite their perfect start to season 2013-14 and their drought-breaking win against their more illustrious neighbours in last season's Copa del Rey Final.
Atletico beat Real 2-1 in extra-time in the Spanish Cup final back in May - their first win at Real's famous Santiago Bernabeu Stadium and their first win against Real in any fixture in 26 matches dating way back to a La Liga victory in 1999.
However, despite that win and the fact that Atletico have won all six matches so far in the new season - to be sitting behind leaders Barcelona on goal difference only - Diego Simoene's team are rank outsiders for Saturday night's huge clash.
Real - who sit third on the La Liga table with five wins and one draw [away to fourth-placed Villareal] so far this season - are the $1.61 favourites at bet365.
Real - with Carlo Ancelotti now in charge following Jose Mourinho's move to Chelsea at the end of last season - looked in awesome form in their recent 6-1 demolition of Turkish side Galatasaray in Istanbul on matchday one of the UEFA Champions League.
But Atletico - winners of the Europa League in 2010 and 2012 - also made an impressive step-up to the Champions League on matchday one with a 3-1 home win over Zenit.
The one certainty of the Madrid derby - which will kick-off on Sunday morning [Australian time] - is that there is likely to be goals galore.
Atletico have scored 18 in six league games to date while Real have scored 14 and their past 12 head-to-head meetings have produced 40 goals at a rate of better than three-per game.
So is it any wonder bet365 are offering just $1.47 on there being more than 2.5 goals scored in Saturday's fixture, which does look the obvious stand-out bet in this match, compared to just $2.60 on there being two goals or less scored in the match?
As is the case in virtually every Real Madrid fixture, their superstar winger Cristiano Ronaldo - fresh from a hat-trick in the Galatasaray rout - is the $3.60 favourite to score the game's opening goal at bet365 and is as short as $1.50 at score at any stage.
But Atletico are one of the most improved teams in Europe in recent seasons and with the confidence of last season's drought-breaking Copa del Rey Final victory are more than capable of holding Real to a draw in this one.
And if you are backing the draw, why not go for a high-scoring one at that with a 2-2 draw priced at $11 in correct score betting at bet365.
*Note prices subject to change