United have the advantage and are at home, but it is Ronaldo's Real Madrid that are instead the favourites going into the second leg of their Champions League tie
The money is coming for Cristiano Ronaldo to make a memorable return to Old Trafford on Tuesday [Wednesday morning Australian time], with Real Madrid now favourites to eliminate Manchester United from the Champions League.
After the first leg ended in a 1-1 draw at the Santiago Bernabeu in February, United were favourites to progress to the quarter-finals - particularly with the second leg to come at home.
Even a 0-0 draw on Tuesday would be enough to see 2008 champions United progress to the last eight at the expense of the record nine-time competition winners.
But after two wins over great rivals Barcelona in the space of five days, Jose Mourinho's revitalised team now find themselves favourites to triumph at Old Trafford and eliminate the runaway English Premier League leaders.
Real, despite still sitting a distant 11 points behind Barcelona in third place in La Liga, are even shorter at the Eskander's Betstar at $2.16 and the TAB at $2.25, where United are priced at $3.15 and $2.75 respectively.
The draw is paying $3.50 at Betstar and $3.60 at the TAB.
|Manchester United to win v Real Madrid at $3.30 at Betfair
||Manchester United to win 2-1 v Real Madrid at $12.50 at Betfair
Betfair's Daniel Bevan said Real Madrid have attracted around 55 percent of money wagered on Tuesday's game, with United only having attracted about 30 percent of money.
Ronaldo was the darling of United fans during his spell at Old Trafford from 2003 to 2009, when he scored 84 goals in 196 Premier League matches and led the side to Champions League glory in 2008.
This will be his first visit back to the ground since joining Real Madrid in June 2009.
But that is good value considering Ronaldo is as short as $1.72, with van Persie at $2, to score at sportsbet.com.au.
The Real Madrid and ex-United superstar is also the $5.60 favourite to score the game's opening goal at Betfair ahead of van Persie at $6.60 and Wayne Rooney at $8.60, with Real Madrid's Karim Benzema - fresh from scoring the opening goal in the win over Barcelona on Saturday - good value at $9.
While another 1-1 draw [which would send the second leg into extra-time] is the favoured option in correct-score betting at Betfair at odds of $8.40, we fancy United to pinch the second leg 2-1 -with Ronaldo naturally scoring for Real Madrid - at the tempting odds of $12.50.
In the other game on Tuesday, German champions Borussia Dortmund should progress to the quarter-finals at the expense of Ukraine's Shakhtar Donetsk, after the first game ended 2-2.
Dortmund, who only need a 0-0 or even a 1-1 draw at home to advance, are the $1.65 favourites at Betfair to win the second leg, with the visitors priced at $5.90 at Betfair and the draw at 90 minutes at $4.30.
*Note prices are subject to change