The reigning champions have won just three of their past seven league outings, and travel to Old Trafford on Monday to face a team unbeaten since November 17.
And Mancini acknowledged United’s impressive run of form - the league leaders are currently on an 18-game unbeaten streak which includes 16 victories - but has urged his squad to not give up on the title and aim to close the gap before the end of the season.
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"United have played very well and won a lot of games. They are unbeaten in their last 18 games in the Premier League. Their last defeat was at Norwich. So they deserve to stay at the top. But not by 15 points. It's not a true table.
"Now we have eight games left. If we play well and win a lot of those games, maybe we can reduce the gap. This should be our target at the moment."
The Italian also spoke of his delight that influential midfielder Yaya Toure signed a new four-year contract on Thursday, branding the Ivorian as "one of the best players in the world".
"I am happy because for me Yaya is one of the best players in the world," Mancini continued.
"He's very important to this club. Yaya is a player who can play to 36 or 37, because he can play in central defence or just in front of the defence."