The South Australian side have lost just once in their last eight matches, climbing to fifth on the table, just three points back from the third-placed Mariners.
Josep Gombau's hosts are priced at $2.25 at bet365 to win at Coopers Stadium on Friday night, where the draw is paying $3.25.
Central Coast meanwhile come into this game off the back of a painful 3-1 loss at home to Melbourne Victory, and are out to $3.25 to win.
Adelaide kick-started their good run of form with a thumping 4-0 win at home to the Mariners in December, and you can get a lengthy $41.00 on them repeating the feat this weekend.
If you fancy the Mariners to hold their own early on, a half-time draw and full-time Adelaide win is paying $5.50.
Reds frontman Bruce Djite looks a little short at $6.50 to open the scoring, with playmaker Marcelo Carrusca a better value bet at $12.00 to find the back of the net first in the game.
Matt Simon at $8.50 is the shortest priced Mariner in that market, with new South Korean playmaker Kim Seung-Yong paying $4.33 to score at any time in what could be his Central Coast debut.