Playing in his third consecutive World Cup, Bresciano is considered a vital cog in a young Socceroo side.
Against an expected high pressing Chile, Bresciano's composure on the ball and ability to pick out Australia's quick forwards could be key in this intriguing battle.
Despite suffering from a back complaint, the 34-year-old Al Gharafa midfielder is looking good, according to his coach.
"Bresciano is ready to go, there is no doubt about that," Postecoglou said.
Socceroo captain Mile Jedinak praised the preparation of the team with all players, including himself after a groin complaint on the last day of the EPL season, fit and ready for Chile.
"We've been preparing very well and working hard as a group. We've come together as one as a group," Jedinak said.
"We'll all be ready to go tomorrow."
Speaking after the Socceroos had their allotted training time on the Arena Pantanal pitch in Cuiaba, the Australian coach however was full of praise for his opponent.
He described Chile's recent progress as something the Socceroos should aspire to.
"Long may our football progress but that's all secondary to making sure we represent our country well tomorrow," Postecoglou said.
"Chile are a good example of a country who have worked to become a force in world football and that is our goal.
"They've worked hard in the last four or five years and we want to be spoken of like people speak of Chile.
"And I'm sure they've done their homework on us and look to nullify our threats.
"It's a World Cup and the pressure and expectations will be enormous, particularly for Chile."