Last year's surprise winners Zambia will be looking to retain their title in South Africa, with the tournament finally getting under way on SaturdaySouth Africa and Cape Verde, with Angola and Morocco to follow later on.
Teams such as Nigeria, Ghana and Cote d'Ivoire start the tournament as favourites, but Zambia showed last year that anything is possible at the Afcon as they won their first ever title after by beating Didier Drogba & Co. in the final.
The Zambians will have to deal with the Super Eagles, Burkina Faso and Ethiopia in Group C if they are to repeat last year's success.
Drogba's Cote d'Ivoire are paired with Tunisia, Algeria and Togo in Group D, while Ghana meet Mali, Niger and DR Congo in Group B.
Meanwhile, record-winners Egypt, who have claimed the title seven times, failed to qualify for the finals this time around.
The top two teams of each group qualify for the quarter-finals, which will be held on February 2 and February 3. The semi-finals will then be held on February 6, with the showpiece taking place four days later in Johannesburg.
Goal.com offers live commentaries for each game, as well as previews, reports and reactions as the tournament progresses.