The Italy international will miss Wednesday's match due to suspension, but has stressed that the Bianconeri will be aiming for victory
The Serie A champions need one point in order to book their ticket for the knockout stages, while their opponents will secure top spot in Group E with a draw.
"A draw is not what we're after. It's a risk for both teams to play for a draw. We have to go there to play our own game and try to win the match," Marchisio was quoted as saying by Tuttosport.
"We are aware of their quality. They sit atop of the group and are the strongest team we have faced so far. It's true that we put in a great performance against Chelsea, but we aren't there yet.
"It will not be an easy game and we will have to put in a performance similar to the one against Chelsea. We have to remain cautious and cannot let them surprise us."
Marchisio will miss the crunch clash in Donetsk due to suspension after picking up his third yellow card of the campaign against Chelsea on matchday 5.