The Italian striker is in hot water with the European governing body following his controversial remarks about gay footballers last month at a press conference during Euro 2012
The 30-year-old sparked angry comments from gay rights activists after claiming he hoped that there were no gay players in Italy's Euro 2012 squad.
He later apologised for his remarks and insisted he was not homophobic, but his portrayal of homosexuals in a negative light has put him in trouble with Uefa.
"Following the opening of disciplinary proceedings against Italy's Antonio Cassano for a discriminatory press statement during Euro 2012, the Uefa Control and Disciplinary Body has decided to impose a fine of €15,000 on the player," read a Uefa statement on Friday.
"An appeal can be lodged against this decision within three days of the dispatch of the full, written decision."