Both sides could be missing some big names. So - faced with their own form worries - how will they contend in the heat at nib Stadium on Saturday?
Pantelidis, Thwaite, Van d. Brink, Jamieson
Dodd, O'Neill, Burns, Nagai
Franjic, Jurman, Donachie, Brown
Murdocca, Brattan, LambadaridisBroich, Halloran, Nichols
Bothh last season's A-League grand finalists head into Saturday's fixture undermanned and desperate for victory after a dreadful start to 2013.
Perth Glory have not won this year with just a draw from three matches, while reigning champions Brisbane Roar have notched one victory from four games in 2013.
That win came back on New Year's Day, however, and Brisbane have now lost three on the trot, slumping to second bottom on the A-League ladder.
The Roar gave up a first-half lead at home last Sunday as Western Sydney stormed back to win 2-1, and Brisbane were further hit with after Besart Berisha and Shane Stefanutto both received their fifth yellow cards of the season, meaning they will miss the trip to Perth.
Jade North is still not match fit and will not travel, while Jack Hingert is back in the squad but it is teenager Corey Brown who will likely take the place of Stefanutto.
Brisbane head coach Mike Mulvey has had to get creative to find a replacement for Berisha.
Mulvey made it clear before the January transfer window that he wanted to sign a new striker but having thus far failed to do so, the Manchester-born manager has no obvious understudy for Berisha.
It will be Ben Halloran who moves central, having played all of his season in a wide attacking position.
Perth could be missing defenders Bas van den Brink and Steve Pantelidis, meaning Michael Thwaite has been rushed back into the squad. He is no certainly to be fit to start, however, while midfielder Liam Miller is suspended.Still, do not expect too many goals at nib Stadium on Saturday.
Perth are the worst attacking team in the A-League this season with just 18 goals in 17 games, while Brisbane will be missing their leading striker.
With Glory's injury issues in defence and the Roar having kept just three clean sheets this campaign, both sides seem to have equal problems heading into Week 18. The points may fall for whoever can cope best.